When industrialist Norman Osborne injected himself with his experimental Goblin Formula, it granted him incredible strength, speed, and resilience but fractured his mind, turning him into the cackling, psychotic terror known as the Green Goblin. Obsessed with power, the Green Goblin rains chaos and destruction upon any who dare oppose his plans for domination, and he holds a very personal vendetta against Spider-Man, who has served as a constant thorn in his side.

Thanks to his access to the impressive weapons technology of Oscorp, the Green Goblin goes to battle outfitted with an array of deadly high-tech gear. Ruthless and unremorseful, the Green Goblin will never stop until he stands supreme.

When the Red Skull sought an heir for his criminal empire, he fathered Sinthea Schmidt. The girl was raised with constant indoctrination of her father’s twisted views. Forced to undergo physical transformation in one of the Red Skull’s machines, she was gifted with superhuman powers. With her partner Crossbones and an incarnation of the Serpent Squad by her side, Sin has rampaged across the world, coming into conflict with the Avengers, S.H.I.E.L.D., and the Winter Soldier. As a child, Ophelia Sarkissian was taken by Hydra and raised by Daniel Whitehall, the mysterious agent known as Kraken. For over two decades, she trained to become one of the organization’s most proficient soldiers. Later in life, she abandoned Hydra to become the leader of the Serpent Squad mercenaries, where she used her peak physical conditioning, cunning, and ruthlessness to secure her place as a deadly viper in the global underworld.